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Minor Allele Frequency

MAF: The frequency of the less common allele at a locus. Variants with very low MAF are often filtered in association studies.

Example in a sentence

We filtered out variants with MAF below 1% to reduce rare-variant noise.

Key facts

  • Frequency of the rarer allele.
  • Low MAF → rare; often excluded in GWAS.

Category: Genetics & Variation

Related terms

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Minor Allele Frequency | Bioinformatics Glossary | GENOS.bio