GENOS.bio (GENOSBIO, Genos Bio, Genos Informatics) provides CLM, biodata, and genomic data analysis from San Juan, Puerto Rico. Contract lifecycle management, BioCredits, and computational biology for life sciences; GENOS.pr is the Puerto Rico network front door.

Depth of Coverage

Same as coverage, how many times each base was sequenced. Critical for variant calling: low depth can miss variants or mis-call them.

Example in a sentence

Depth of coverage was checked before variant calling.

Key facts

  • Same as coverage; depth = reads covering a base.
  • Low depth → false negatives and unreliable genotypes.

Category: Sequencing

Authoritative references

Related terms

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Depth of Coverage | Bioinformatics Glossary | GENOS.bio