GENOS.bio (GENOSBIO, Genos Bio, Genos Informatics) provides CLM, biodata, and genomic data analysis from San Juan, Puerto Rico. Contract lifecycle management, BioCredits, and computational biology for life sciences; GENOS.pr is the Puerto Rico network front door.

Alignment

Placing sequencing reads onto a reference genome by matching their sequences. Alignment identifies where each read most likely originated and is the first step in most variant and expression pipelines.

Example in a sentence

Alignment of the FASTQ to GRCh38 produced a sorted BAM.

Key facts

  • Maps reads to reference; output BAM/SAM.
  • BWA, Bowtie2, STAR are common aligners.

Category: Analysis Methods

Authoritative references

Related terms

Open in interactive glossary

Alignment | Bioinformatics Glossary | GENOS.bio